While getting ready for Halloween and searching for a skull left behind by Scream Street's first skeleton resident, Luke is recruited, along with his companions Resus and Cleo, to help the famous Headless Horseman find his stolen head.

"Opening a doorway out of Scream Street seems to have brought with it a whole new set of problems--and now Luke, Resus, and Cleo are beginning to realize what they have unleashed. Scream Street faces a greater threat than ever before--normals!"--

When Luke Watson turns into a werewolf for the third time, he and his parents are moved to Scream Street, where they and other "unusual lifeforms" are trapped unless Luke and his friends can find six powerful relics hidden by the founding fathers before sinister landlord Sir Otto does.

"A new crisis has arisen in Scream Street. Eefa Everwell's niece, Poppy, has been replaced by a changeling! What's more, the real Poppy is being held captive by the evil Crimson Queen. Luke, Resus and Cleo set off to rescue her, but the fairy realm is full of nasty surprises. Then Resus is presented with an offer he can't refuse--and things become a whole lot more complicated..."--From publisher description.

One week after arriving on Scream Street, Luke Watson is even more determined to find the six relics that will let him return home, but he and his friends must first face problems with the vampires' vital blood supply and with raging sewer rats.